Description

[1,1-Biphenyl]-2,2-Diol,6,6-Dimethyl-,(1R)-(9Ci) is a chiral biphenyl derivative, specifically the (1R)-enantiomer, characterized by its diol and dimethyl substituents. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, where its defined stereochemistry is critical for producing enantiomerically pure products. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), asymmetric catalysts, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of sophisticated ligands for metal-catalyzed asymmetric reactions, such as hydrogenation or cross-coupling.
• Advanced Organic Synthesis: Serves as a versatile building block for constructing complex, stereodefined molecular architectures in medicinal and process chemistry.
• Material Science Research: Potential monomer or modifier in the development of chiral polymers or advanced organic materials with specific optical properties.
• Analytical Standard: Employed as a high-purity reference standard for analytical method development and quality control in chiral separations (e.g., HPLC, SFC).

Basic Information

Product Name	[1,1-Biphenyl]-2,2-Diol,6,6-Dimethyl-,(1R)-(9Ci)
CAS No.	10489-16-4
Molecular Formula	C14H14O2
Molecular Weight	214.26 g/mol
Synonyms	(1R)-6,6'-Dimethyl-[1,1'-biphenyl]-2,2'-diol; (R)-6,6'-Dimethylbiphenyl-2,2'-diol; (R)-(-)-6,6'-Dimethyl-2,2'-dihydroxybiphenyl; (R)-BINOL derivative; (R)-2,2'-Dihydroxy-6,6'-dimethyl-1,1'-biphenyl; (R)-6,6'-Dimethyl-2,2'-biphenyldiol; Light-sensitive (store away from light)
EINECS	Contact for details

Quality Control

Our [1,1-Biphenyl]-2,2-Diol,6,6-Dimethyl-,(1R)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing identity, purity, and chiral excess data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.