Description

(1R,2R)-2-Methylcyclopropane-1-Carboxylic Acid CAS NO 10487-86-2 is a high-purity, chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its rigid, strained three-membered ring structure and defined stereochemistry, enabling the precise construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Asymmetric Catalysis & Ligand Design: Serves as a precursor for chiral ligands and catalysts used in enantioselective synthesis to produce single-isomer compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique structural properties.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing specific aroma chemicals and flavor compounds.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic routes.

Basic Information

Product Name	(1R,2R)-2-Methylcyclopropane-1-Carboxylic Acid
CAS No.	10487-86-2
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(1R,2R)-2-Methylcyclopropanecarboxylic Acid; (1R,2R)-2-Methylcyclopropane-1-Carboxylic Acid; (1R,2R)-2-Methylcyclopropanecarboxylic Acid; trans-2-Methylcyclopropanecarboxylic Acid; (1R,2R)-trans-2-Methylcyclopropanecarboxylic Acid; (1R-cis)-2-Methylcyclopropanecarboxylic Acid; 2-Methylcyclopropanecarboxylic Acid, (1R,2R)-; Cyclopropanecarboxylic acid, 2-methyl-, (1R,2R)-
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Methylcyclopropane-1-Carboxylic Acid is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.