Description

4-Hydroxy-3-Nitrophenylacetic Acid is a specialized aromatic compound featuring both phenolic and carboxylic acid functional groups, making it a versatile intermediate for advanced chemical synthesis. Its molecular structure is critical for creating complex molecules where precise substitution patterns are required. This high-purity intermediate is essential for research and production in the pharmaceutical and fine chemical industries, where it serves as a key building block for active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring nitrophenol or phenylacetic acid motifs.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, pesticides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing azo dyes and other high-performance colorants.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialty chemicals for research and industrial applications.
• Biochemical Research: Utilized as a standard or reagent in research laboratories studying enzyme inhibitors or metabolic pathways.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific chemical properties.

Basic Information

Product Name	4-Hydroxy-3-Nitrophenylacetic Acid
CAS No.	10463-20-4
Molecular Formula	C8H7NO5
Molecular Weight	197.14 g/mol
Synonyms	2-(4-Hydroxy-3-nitrophenyl)acetic Acid; (4-Hydroxy-3-nitrophenyl)acetic Acid; 3-Nitro-4-hydroxyphenylacetic Acid; 4-Hydroxy-3-nitrobenzeneacetic Acid; 2-(4-Hydroxy-3-nitrophenyl)ethanoic Acid; 4-Hydroxy-3-nitrophenylacetic Acid; 4-Hydroxy-3-nitro-α-toluic Acid
EINECS	233-943-9

Quality Control

Our 4-Hydroxy-3-Nitrophenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency for use in sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. The product may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.