Description

4-(Chloromethyl)Pyridine is a versatile and reactive organic intermediate featuring a pyridine ring substituted with a chloromethyl group. This bifunctional structure makes it a critical building block for synthesizing more complex molecules in advanced chemical manufacturing. It is essential for research chemists and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyridine-based pharmacophores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the pyridine moiety enhances biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating complex ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research to explore new molecular entities.
• Functional Polymer Modification: Employed to introduce pyridine functionality into polymers, altering their chemical and physical properties.
• Cross-coupling Reactions: Acts as an electrophilic component in various palladium-catalyzed cross-coupling reactions for C-C bond formation.

Basic Information

Product Name	4-(Chloromethyl)Pyridine
CAS No.	10445-91-7
Molecular Formula	C6H6ClN
Molecular Weight	127.57 g/mol
Synonyms	4-Picolyl Chloride; 4-(Chloromethyl)pyridine; γ-Picolyl Chloride; 4-Pyridylmethyl Chloride; 4-Chloromethylpyridine; Picolyl Chloride; 4-Pyridinemethanamine, N-(4-chlorophenyl)-N-methyl-; (4-Pyridinyl)methyl Chloride
EINECS	233-943-5

Quality Control

Our 4-(Chloromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and reactivity, it is recommended to use the material promptly after opening the original container.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.