Description

1-Methylpyrrolidine-2-Thione is a versatile organosulfur compound with a thiocarbonyl functional group, serving as a critical building block and reagent in advanced chemical synthesis. Its value lies in its unique reactivity as a sulfur donor and heterocyclic scaffold, enabling the development of novel compounds with specific properties. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing modified pyrrolidine or thioamide moieties.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the thiocarbonyl group can contribute to biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for generating specialized ligands in coordination chemistry and catalysis.
• Organic Synthesis Reagent: Employed as a sulfur-transfer agent or as a heterocyclic building block in complex multi-step synthetic routes.
• Material Science Research: Investigated for the preparation of functional polymers or organic electronic materials due to its electron-rich sulfur atom.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for methodological studies and new reaction development.

Basic Information

Product Name	1-Methylpyrrolidine-2-Thione
CAS No.	10441-57-3
Molecular Formula	C5H9NS
Molecular Weight	115.20 g/mol
Synonyms	1-Methyl-2-pyrrolidinethione; 1-Methyl-2-pyrrolidinone thioamide; 1-Methyl-2-thioxopyrrolidine; N-Methyl-2-pyrrolidinethione; N-Methyl-2-thioxopyrrolidine; 2-Thioxo-1-methylpyrrolidine; 1-Methylpyrrolidine-2-thiol (tautomer); NSC 5239
EINECS	233-941-5

Quality Control

Our 1-Methylpyrrolidine-2-Thione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment. We support compliance with global regulatory frameworks, and our quality systems are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.