Description

2-Chloromandelic Acid is a versatile chiral organic compound that serves as a key intermediate in the synthesis of complex molecules. Its value lies in its bifunctional structure, featuring both a carboxylic acid and a hydroxyl group on a chlorinated aromatic ring, making it a valuable building block for pharmaceuticals and fine chemicals. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where its chlorinated mandelic acid structure contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Building Block: Employed in the research and production of complex organic molecules, dyes, and specialty polymers.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway research due to its specific stereochemistry.

Basic Information

Product Name	2-Chloromandelic Acid
CAS No.	10421-85-9
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	(±)-2-Chloromandelic Acid; DL-2-Chloromandelic Acid; 2-Chloro-2-hydroxy-2-phenylacetic Acid; α-Chloromandelic Acid; (RS)-2-Chloromandelic Acid; o-Chloromandelic Acid; Mandelic acid, 2-chloro-; 2-Chloro-α-hydroxybenzenacetic acid
EINECS	233-902-8

Quality Control

Our 2-Chloromandelic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat. The product may be hygroscopic; ensure containers are sealed after use to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Reported on COA
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.