Description

2-Bromo-3-Methylbutyric Acid is a versatile halogenated carboxylic acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in the reactive bromine atom and the carboxylic acid functionality, which allow for selective transformations and the introduction of the branched 3-methylbutyric acid moiety. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key starting material or chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a branched alkyl chain.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the bromine atom facilitates further coupling reactions.
• Organic Synthesis Building Block: Employed in peptide mimetics, esterification reactions, and as a precursor for other functionalized derivatives via nucleophilic substitution of the bromine.
• Ligand and Catalyst Preparation: Useful for synthesizing chiral ligands or metal-organic complexes for asymmetric catalysis.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialized polymers and fine chemicals.

Basic Information

Product Name	2-Bromo-3-Methylbutyric Acid
CAS No.	10323-40-7
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	2-Bromo-3-methylbutanoic acid; (±)-2-Bromo-3-methylbutyric acid; 3-Methyl-2-bromobutyric acid; α-Bromo-β-methylbutyric acid; DL-2-Bromo-3-methylbutyric acid; NSC 404058; 2-Bromoisovaleric acid (common misnomer, check structure); Bromo-methylbutanoic acid
EINECS	233-700-0

Quality Control

Our 2-Bromo-3-Methylbutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, identity confirmation, and impurity profiling, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, as the compound is a strong acid/organic solvent. Keep container tightly sealed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.470 - 1.480
Specific Gravity (20°C)	1.45 - 1.55

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.