Description

5-Phenyl-4,5-dihydroisoxazole-3-carboxylic acid is a versatile heterocyclic building block of significant interest in synthetic organic chemistry. Its core structure, featuring a fused isoxazoline ring, makes it a valuable precursor for the development of novel pharmacologically active compounds and advanced materials. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with potential for improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, including cycloaddition reactions and heterocycle functionalization.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring this specific isoxazoline carboxylic acid scaffold.

Basic Information

Product Name	5-Phenyl-4,5-dihydroisoxazole-3-carboxylic Acid
CAS No.	10313-27-6
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	3-Isoxazolecarboxylic acid, 4,5-dihydro-5-phenyl-; 5-Phenyl-2-isoxazoline-3-carboxylic acid; 5-Phenyl-4,5-dihydro-3-isoxazolecarboxylic acid; 5-Phenyl-δ²-isoxazoline-3-carboxylic acid; 3-Carboxy-5-phenyl-4,5-dihydroisoxazole; 5-Phenyl-4,5-dihydro-1,2-oxazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Phenyl-4,5-dihydroisoxazole-3-carboxylic acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.