Description

Methyl (2S)-2-Methylbutanoate is a high-purity chiral ester valued for its distinct, fruity aroma and role as a versatile synthetic building block. This compound is essential for applications requiring precise stereochemistry and consistent organoleptic properties. It is primarily utilized by manufacturers in the flavor & fragrance, pharmaceutical, and fine chemical synthesis industries.

Application

• Flavor & Fragrance (F&F) Industry: A key chiral ingredient for creating sophisticated, natural-tasting fruit flavors (e.g., apple, strawberry) and complex fragrance accords.
• Pharmaceutical Intermediates: Serves as a chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Fine Chemical Synthesis: Used as a building block for producing specialty chemicals, agrochemicals, and liquid crystals where specific stereochemistry is critical.
• Solvent & Carrier: Functions as a high-purity solvent for sensitive reactions or as a carrier for active compounds in various formulations.
• Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new synthetic pathways.
• Food Grade Applications: Where compliant, used as a food-grade flavoring agent in beverages, confectionery, and dairy products.

Basic Information

Product Name	Methyl (2S)-2-Methylbutanoate
CAS No.	10307-60-5
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(S)-Methyl 2-methylbutyrate; (S)-Methyl 2-methylbutanoate; L-Methyl 2-methylbutanoate; Methyl (S)-2-methylbutanoate; (2S)-2-Methylbutanoic acid methyl ester; Methyl (S)-2-methylbutyrate; Appleate (trade name); FEMA 2719
EINECS	233-682-2

Quality Control

Our Methyl (2S)-2-Methylbutanoate is produced under strict quality management systems. Each batch is tested to ensure high chemical and optical purity, meeting the stringent requirements of the flavor, fragrance, and pharmaceutical sectors. A comprehensive Certificate of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at 15-25°C. Due to its highly volatile nature, keep away from heat, sparks, and open flames. Ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain quality.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% (S-isomer)
Refractive Index (20°C)	1.395 - 1.399
Specific Gravity (20/20°C)	0.870 - 0.880

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.