Description

4-Cyclobutylphenol is a versatile organic compound featuring a phenolic group attached to a cyclobutyl ring, offering unique steric and electronic properties. This structural motif makes it a valuable advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging its phenolic functionality.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its rigid, planar structure.
• Polymer Modification: Acts as a monomer or chain terminator in the synthesis of specialty polymers, such as polycarbonates and epoxy resins, to alter thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce the cyclobutylphenol moiety into more complex molecules.
• Fragrance & Flavor Chemistry: Utilized as a starting material for synthesizing specific aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	4-Cyclobutylphenol
CAS No.	10292-59-8
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	p-Cyclobutylphenol; Phenol, 4-cyclobutyl-; 4-(Cyclobutyl)phenol; 1-(4-Hydroxyphenyl)cyclobutane; Cyclobutyl-4-phenol; 4-Hydroxy-1-cyclobutylbenzene; 4-Cyclobutyl-1-hydroxybenzene; 10292-59-8
EINECS	Contact for details

Quality Control

Our 4-Cyclobutylphenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.