Description

Benzene, 1,4-Bis(Bromomethyl)-2-Chloro- is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl and chloro substituents, makes it a critical precursor for constructing complex molecules, particularly in pharmaceutical and materials science research. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug candidates, particularly for constructing fused ring systems and targeted molecular scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its halogenated structure allows for further functionalization.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Polymer and Material Science: Employed in the creation of monomers for high-performance polymers, liquid crystals, and other advanced materials with specific electronic or thermal properties.
• Cross-coupling Reactions: The bromomethyl groups are excellent substrates for various palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, enabling carbon-carbon bond formation.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	Benzene, 1,4-Bis(Bromomethyl)-2-Chloro-
CAS No.	10221-09-7
Molecular Formula	C8H7Br2Cl
Molecular Weight	298.40 g/mol
Synonyms	1,4-Bis(bromomethyl)-2-chlorobenzene; 2-Chloro-1,4-bis(bromomethyl)benzene; 2-Chloro-p-xylene-α,α'-dibromide; α,α'-Dibromo-2-chloro-p-xylene; 2-Chloro-α,α'-dibromo-p-xylene; 1-Chloro-2,5-bis(bromomethyl)benzene; p-Xylene, 2-chloro-α,α'-dibromo-
EINECS	Contact for details

Quality Control

Our Benzene, 1,4-Bis(Bromomethyl)-2-Chloro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.