Description

Methylthioacetylene is a highly reactive organosulfur building block characterized by its alkyne and thioether functionalities. This compound is of significant value in advanced organic synthesis, particularly for constructing complex sulfur-containing heterocycles and as a key intermediate in pharmaceutical and agrochemical research. It is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries seeking to introduce methylthioacetylene units into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon for the development of novel active pharmaceutical ingredients (APIs), especially those containing thioether or acetylene motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the methylthioacetylene group imparts specific biological activity.
• Material Science: Acts as a monomer or precursor in the synthesis of specialized polymers and advanced materials with unique electronic or structural properties.
• Ligand & Catalyst Development: Employed in the preparation of sulfur-containing ligands for metal catalysis and coordination chemistry.
• Chemical Research: A versatile reagent for [3+2] cycloadditions, cross-coupling reactions, and other methodologies to build complex molecular architectures.

Basic Information

Product Name	Methylthioacetylene
CAS No.	10152-75-7
Molecular Formula	C3H4S
Molecular Weight	72.13 g/mol
Synonyms	Methylthioethyne; Propargyl methyl sulfide; (Methylthio)ethyne; Methyl ethynyl sulfide; 3-(Methylthio)-1-propyne; 1-Methylthio-1-propyne; Methylsulfanylacetylene; Methanethiol, ethynyl-
EINECS	233-410-7

Quality Control

Our Methylthioacetylene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, GC-MS, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, preferably at 2-8°C. Keep away from heat, sparks, open flames, and oxidizing agents. Containers should be kept tightly sealed and upright to prevent leakage and pressure build-up.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (GC Area %)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.