Description

(2S,3S)-2-Amino-3-Hydroxy-Pentanoic Acid CAS NO 10148-66-0 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific (2S,3S) stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the production of complex molecules with precise stereochemical control. It is essential for research and development in the pharmaceutical industry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the research and development of novel peptides and peptide mimetics with specific biological activities.
• Chiral Catalyst & Ligand Synthesis: Serves as a precursor for synthesizing chiral auxiliaries, catalysts, and ligands used in asymmetric catalysis.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies and enzyme-substrate interaction research.
• Agrochemical Development: A potential intermediate for creating chiral herbicides, fungicides, or plant growth regulators.
• Fine Chemical Synthesis: A versatile building block for synthesizing specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	(2S,3S)-2-Amino-3-Hydroxy-Pentanoic Acid
CAS No.	10148-66-0
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,3S)-3-Hydroxy-L-norvaline; L-threonine homologue; (2S,3S)-2-Amino-3-hydroxypentanoic acid; allo-Threonine homologue; (2S,3S)-3-Hydroxynorvaline; β-Hydroxy-norvaline; 2-Amino-3-hydroxypentanoic acid (2S,3S)-isomer
EINECS	Contact for details

Quality Control

Our (2S,3S)-2-Amino-3-Hydroxy-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (2S,3S)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.