Description

(1R,2S)-Rel-1,2-Cyclohexanediamine Hydrochloride CAS NO 10027-80-2 is a high-purity chiral diamine salt, serving as a critical building block and chiral ligand in asymmetric synthesis. Its value lies in providing exceptional enantioselectivity and stability for the production of complex pharmaceutical intermediates and fine chemicals. This product is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of a stereochemically defined diamine derivative.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for transition metal catalysts in enantioselective hydrogenation, cyclization, and cross-coupling reactions.
• Fine Chemical Synthesis: Employed in the preparation of complex molecules for agrochemicals, flavors, and fragrances where stereochemical control is paramount.
• Resolution Agent: Acts as a chiral resolving agent for the separation of racemic mixtures of carboxylic acids and other acidic compounds.
• Polymer Modification: Serves as a monomer or cross-linking agent for specialty polymers requiring specific stereochemistry and enhanced thermal stability.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and chiral space.

Basic Information

Product Name	(1R,2S)-Rel-1,2-Cyclohexanediamine Hydrochloride
CAS No.	10027-80-2
Molecular Formula	C6H14N2·HCl
Molecular Weight	150.65 g/mol
Synonyms	(1R,2S)-(-)-1,2-Diaminocyclohexane Monohydrochloride; (1R,2S)-(-)-DACH·HCl; rel-(1R,2S)-1,2-Cyclohexanediamine Hydrochloride; (-)-trans-1,2-Diaminocyclohexane Hydrochloride; (1R,2S)-1,2-DACH·HCl; (1R,2S)-Cyclohexane-1,2-diamine Hydrochloride; (1R,2S)-1,2-Diaminocyclohexane Hydrochloride; trans-(1R,2S)-1,2-Diaminocyclohexane Monohydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2S)-Rel-1,2-Cyclohexanediamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical assay, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.