Description

Sodium Methanethiosulphonate is a versatile organosulfur compound with significant utility in organic synthesis and biochemical research. Its primary value lies in its role as a key reagent for the specific modification of cysteine residues in peptides and proteins, enabling advanced structural and functional studies. This makes it an essential material for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors who require precise chemical tools for molecular design and analysis.

Application

• Bioconjugation & Protein Engineering: A critical reagent for the site-specific modification of cysteine thiol groups in peptides, proteins, and antibodies for drug conjugation (ADC development) and labeling.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs that leverage sulfur chemistry for targeted activity.
• Agrochemical Synthesis: Serves as a building block in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a modifier or chain-transfer agent in the synthesis of specialty polymers and functional materials.
• Biochemical Research: Employed in studies of enzyme mechanisms, redox biology, and the structure-function relationships of biomolecules.
• Cross-linking Agent: Utilized for creating disulfide-like bridges or introducing specific functional groups into macromolecular structures.

Basic Information

Product Name	Sodium Methanethiosulphonate
CAS No.	1950-85-2
Molecular Formula	CH3NaO2S2
Molecular Weight	138.16 g/mol
Synonyms	Sodium Methyl Thiosulfonate; Methanesulfonothioic Acid Sodium Salt; Methyl Methanethiosulfonate Sodium Salt; S-Methyl Methanethiosulfonate Sodium Salt; Sodium S-Methyl Thiosulfate; MTSSNa; Contact for additional synonyms.
EINECS	217-805-0

Quality Control

Our Sodium Methanethiosulphonate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identification (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.