Description

5-Methyl-2-thiophenecarboxylic acid is a versatile heterocyclic building block featuring a carboxylic acid functional group on a substituted thiophene ring. This compound matters as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure imparts specific electronic and steric properties. It is needed by research chemists and process development teams in fine chemical, pharmaceutical, and material science industries for constructing active pharmaceutical ingredients (APIs), ligands, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiophene moiety can enhance biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials.
• Chemical Research & Development: A valuable building block for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for specialized chemical orders.

Basic Information

Product Name	5-Methyl-2-thiophenecarboxylic Acid
CAS No.	1918-79-2
Molecular Formula	C7H6O2S
Molecular Weight	154.19 g/mol
Synonyms	5-Methylthiophene-2-carboxylic Acid; 2-Carboxy-5-methylthiophene; 5-Methyl-2-thiophenecarboxylic acid; 5-Methylthiophene-2-carboxylic acid; 5-Methyl-2-thiofencarboxylic Acid; 2-Thiophenecarboxylic acid, 5-methyl-; 5-Methyl-2-thiophene carboxylic acid
EINECS	217-639-8

Quality Control

Our 5-Methyl-2-thiophenecarboxylic Acid is produced under strict quality management protocols. We offer various purity grades, including standard and high-purity (>98% HPLC), to meet diverse R&D and production needs. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems ensure traceability and consistency, supporting compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.