Description

4-Bromophenylacetic Acid is a versatile brominated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive bromine substituent and the acetic acid side chain, which allow for selective functionalization and coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to create complex molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators, leveraging the phenylacetic acid moiety.
• Liquid Crystal & OLED Material Production: Acts as a starting material for synthesizing brominated aromatic cores essential for electronic and photonic materials.
• Peptide Mimetics & Bioconjugation: The carboxylic acid group facilitates coupling reactions to create peptide analogs or for labeling biomolecules.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis & Research: A valuable reagent for introducing the 4-bromophenyl moiety into more complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	4-Bromophenylacetic Acid
CAS No.	1878-68-8
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	(4-Bromophenyl)acetic Acid; 2-(4-Bromophenyl)acetic Acid; p-Bromophenylacetic Acid; 4-Bromobenzeneacetic Acid; NSC 404108; p-Bromophenylethanoic Acid; 4-Bromo-α-toluic Acid; 4-Bromobenzylcarboxylic Acid
EINECS	217-524-3

Quality Control

Our 4-Bromophenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances. Our production facilities adhere to cGMP guidelines where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	113°C - 117°C
Loss on Drying	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.