Description

Isopropoxytrimethylsilane is a versatile organosilicon compound widely used as a key reagent and intermediate in advanced chemical synthesis. Its primary value lies in its ability to act as a silylating agent, introducing the trimethylsilyl (TMS) protecting group to alcohols and other functional groups, thereby modifying reactivity and stability. This makes it an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular modifications. Its highly volatile nature also makes it suitable for applications in surface treatment and as a precursor in materials science.

Application

• Silylating Agent: Used to protect hydroxyl groups (-OH) in organic synthesis, particularly in the production of complex pharmaceutical intermediates and fine chemicals.
• Surface Modification: Employed as a coupling agent or surface treatment for silica, glass, and other inorganic materials to impart hydrophobic properties.
• Precursor for Silicones: Serves as a building block in the synthesis of specialized silicone polymers and resins.
• Adhesion Promoter: Used in formulations for coatings, sealants, and adhesives to improve bonding to various substrates.
• Laboratory Reagent: A valuable reagent in research and development for derivatization in analytical chemistry (e.g., GC-MS) and exploratory synthesis.
• Water Scavenger: Utilized in moisture-sensitive chemical reactions to trap trace amounts of water, ensuring reaction efficiency.

Basic Information

Product Name	Isopropoxytrimethylsilane
CAS No.	1825-64-5
Molecular Formula	C6H16OSi
Molecular Weight	132.28 g/mol
Synonyms	Trimethylisopropoxysilane; Isopropyloxytrimethylsilane; (Isopropoxy)trimethylsilane; 1-Isopropoxy-1,1,1-trimethylsilane; Silane, isopropoxytrimethyl-; IPTMS; TMIS; Isopropoxy(trimethyl)silane
EINECS	217-369-5

Quality Control

Our Isopropoxytrimethylsilane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. While typically supplied in technical or reagent grades, our quality management system ensures the product meets the stringent requirements for research and industrial applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and open flame. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and moisture ingress. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Density (20°C)	0.76 - 0.78 g/mL
Refractive Index (n20/D)	1.378 - 1.382
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.