Description

1-Bromo-3-Cyclopropylbenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring a bromine atom and a cyclopropyl group on a benzene ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the cyclopropyl moiety for biological activity.
• Material Science Research: Serves as a monomer or precursor in the creation of specialized polymers and liquid crystals with tailored electronic properties.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl and other complex structures.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and exploring new reaction pathways in organic chemistry.
• Ligand and Catalyst Preparation: Used to synthesize sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Bromo-3-Cyclopropylbenzene
CAS No.	1798-85-2
Molecular Formula	C9H9Br
Molecular Weight	197.07 g/mol
Synonyms	3-Bromophenylcyclopropane; (3-Bromophenyl)cyclopropane; m-Bromophenylcyclopropane; 3-Cyclopropylbromobenzene; 1-Bromo-3-cyclopropyl-benzene; 3-Bromocyclopropylbenzene; Cyclopropyl(3-bromophenyl); Benzene, 1-bromo-3-cyclopropyl-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Cyclopropylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Specific Impurity A	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.