Description

(4As)-5α-[(E)-4-Carboxy-3-Methyl-3-Butenyl]-3,4,4A,5,6,7,8,8A-Octahydro-5,6β,8Aβ-Trimethyl-1-Naphthoic Acid CAS NO 1782-71-4 is a high-purity, complex carboxylic acid derivative with a fused polycyclic structure. This compound serves as a critical advanced pharmaceutical intermediate for the synthesis of novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery. It is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies focused on creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid analogs and terpenoid-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Fine Chemical Synthesis: Serves as a precursor for complex chiral molecules requiring its specific carboxylic acid and olefin functionalities.
• Biochemical Research: Potential use as a probe or standard in studying enzymatic pathways involving polycyclic acid substrates.
• Process Development: Employed in scaling up synthetic routes for potential new drug candidates in pre-clinical and clinical development stages.

Basic Information

Product Name	(4As)-5α-[(E)-4-Carboxy-3-Methyl-3-Butenyl]-3,4,4A,5,6,7,8,8A-Octahydro-5,6β,8Aβ-Trimethyl-1-Naphthoic Acid
CAS No.	1782-71-4
Molecular Formula	C₂₁H₃₂O₄
Molecular Weight	348.48 g/mol
Synonyms	5α-[(E)-4-Carboxy-3-methylbut-3-en-1-yl]-3,4,4a,5,6,7,8,8a-octahydro-5,6β,8aβ-trimethyl-1-naphthoic acid; (4aS)-5-[(E)-4-Carboxy-3-methylbut-3-en-1-yl]-3,4,4a,5,6,7,8,8a-octahydro-5,6,8a-trimethyl-1-naphthoic Acid; 1-Naphthalenecarboxylic acid, 3,4,4a,5,6,7,8,8a-octahydro-5-[(1E)-4-carboxy-3-methyl-3-buten-1-yl]-5,6,8a-trimethyl-, (4aS)-; CAS 1782-71-4; 5α-Carboxyabietic acid derivative; Dihydroabietic acid type derivative
EINECS	Contact for details

Quality Control

Our (4As)-5α-[(E)-4-Carboxy-3-Methyl-3-Butenyl]-3,4,4A,5,6,7,8,8A-Octahydro-5,6β,8Aβ-Trimethyl-1-Naphthoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.