Description

1-[4-(Trifluoromethyl)Phenyl]-2-Thiourea is a specialized thiourea derivative characterized by a trifluoromethylphenyl substituent. This compound is a valuable synthetic intermediate and building block in advanced organic chemistry, offering unique reactivity due to the electron-withdrawing trifluoromethyl group. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the thiourea moiety and fluorine atoms can contribute to biological activity and environmental persistence profiles.
• Organic Synthesis Reagent: Serves as a versatile precursor for heterocyclic compounds, including thiazoles and other sulfur/nitrogen-containing ring systems important in medicinal and materials chemistry.
• Material Science: Investigated as a monomer or additive in the creation of specialty polymers, resins, or metal-chelating agents with specific thermal or chemical resistance properties.
• Chemical Biology Probe: Employed in research to study enzyme inhibition or as a scaffold for developing molecular probes and sensors.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]-2-Thiourea
CAS No.	1736-72-7
Molecular Formula	C8H7F3N2S
Molecular Weight	220.22 g/mol
Synonyms	4-(Trifluoromethyl)phenylthiourea; N-[4-(Trifluoromethyl)phenyl]thiourea; 1-(4-Trifluoromethylphenyl)-2-thiourea; p-Trifluoromethylphenylthiourea; 4-Trifluoromethylphenylthiourea; α-(4-Trifluoromethylphenyl)thiourea; (4-Trifluorophenyl)thiourea; Thiourea, N-[4-(trifluoromethyl)phenyl]-
EINECS	217-085-7

Quality Control

Our production of 1-[4-(Trifluoromethyl)Phenyl]-2-Thiourea adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.