Description

4-Hydroxy-6-Methyl-2-(Trifluoromethyl)Quinoline is a high-value, fluorinated quinoline derivative that serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its unique structure, featuring a trifluoromethyl group, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used as a building block for developing new-generation pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and in organic synthesis as a fluorinated scaffold.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized fluorinated quinoline-based dyes and fluorescent markers.

Basic Information

Product Name	4-Hydroxy-6-Methyl-2-(Trifluoromethyl)Quinoline
CAS No.	1701-20-8
Molecular Formula	C₁₁H₈F₃NO
Molecular Weight	227.18 g/mol
Synonyms	2-(Trifluoromethyl)-6-methylquinolin-4-ol; 6-Methyl-2-(trifluoromethyl)-4-quinolinol; 4-Hydroxy-6-methyl-2-trifluoromethylquinoline; 4-Quinolinol, 6-methyl-2-(trifluoromethyl)-; 6-Methyl-2-trifluoromethylquinolin-4-ol; 1701-20-8; 2-Trifluoromethyl-6-methyl-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-Methyl-2-(Trifluoromethyl)Quinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive pharmaceutical and R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.