Description

Pyrrolidine-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, essential for introducing the pyrrolidine-sulfonyl moiety into target molecules. Its primary value lies in its role as a key sulfonylation reagent and building block in advanced organic synthesis, enabling the creation of complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Sulfonamide Synthesis: Used to prepare a wide variety of sulfonamide derivatives, which are important pharmacophores in many therapeutic agents.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and pesticides by creating bioactive sulfonamide structures.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized to create sulfonyl-based probes for studying protein function and enzyme activity in biological systems.
• Custom Synthesis & Contract Manufacturing: Serves as a key starting material for custom chemical synthesis and scale-up projects under cGMP or ISO standards.

Basic Information

Product Name	Pyrrolidine-1-Sulfonyl Chloride
CAS No.	1689-02-7
Molecular Formula	C4H8ClNO2S
Molecular Weight	153.63 g/mol
Synonyms	1-Pyrrolidinesulfonyl Chloride; N-Sulfonylchloropyrrolidine; Pyrrolidine-1-sulfonyl chloride; Pyrrolidinosulfonyl Chloride; 1-(Chlorosulfonyl)pyrrolidine; Pyrrolidine Sulfonyl Chloride; N-(Chlorosulfonyl)pyrrolidine; NSC 163031
EINECS	Contact for details

Quality Control

Our Pyrrolidine-1-Sulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and ensure maximum shelf life. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.