Description

3,4-Dichloropyridazine CAS NO 1677-80-1 is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. This compound is highly valued for its reactivity, serving as a key intermediate in the development of complex molecules for the pharmaceutical and agrochemical industries. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, leveraging its dichloro-substitution for further functionalization.
• Material Science Research: Serves as a building block for creating specialized ligands, polymers, and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination to create complex biaryl structures.
• Nucleophilic Aromatic Substitution: The chlorine atoms are readily displaced by various nucleophiles, enabling rapid diversification of the pyridazine core.

Basic Information

Product Name	3,4-Dichloropyridazine
CAS No.	1677-80-1
Molecular Formula	C4H2Cl2N2
Molecular Weight	148.98 g/mol
Synonyms	3,4-Dichloro-1,2-diazine; 3,4-Dichloropyridazine; 1,2-Diazine, 3,4-dichloro-; Pyridazine, 3,4-dichloro-; NSC 404087; 3,4-DCP; 3,4-Dichloro-1,2-diazabenzene
EINECS	Contact for details

Quality Control

Our 3,4-Dichloropyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.