Description

3-Benzoylamino-3-(4-Fluoro-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative characterized by its fluorinated aromatic and benzoylated amide structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, or metabolic diseases.
• Peptidomimetic Research: Used to incorporate fluorinated phenylalanine analogs into peptide chains to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides or fungicides, where the fluorine atom can improve lipophilicity and biological activity.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or photoaffinity labels used in proteomics and enzyme inhibition studies.
• Material Science: Potential monomer or additive for specialty polymers where the aromatic and amide functionalities can influence material properties.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and asymmetric catalysis research.

Basic Information

Product Name	3-Benzoylamino-3-(4-Fluoro-Phenyl)-Propionic Acid
CAS No.	1647-94-5
Molecular Formula	C16H14FNO3
Molecular Weight	287.29 g/mol
Synonyms	3-Benzamido-3-(4-fluorophenyl)propanoic acid; N-Benzoyl-4-fluoro-DL-phenylalanine; 3-(Benzoylamino)-3-(4-fluorophenyl)propanoic acid; 4-Fluoro-N-benzoylphenylalanine; (RS)-3-Benzoylamino-3-(4-fluorophenyl)propionic acid; DL-4-Fluoro-N-benzoylphenylalanine; Bz-4-F-Phe-OH; 3-(4-Fluorophenyl)-3-(phenylformamido)propanoic acid
EINECS	Contact for details

Quality Control

We supply 3-Benzoylamino-3-(4-Fluoro-Phenyl)-Propionic Acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles. We adhere to a cGMP-compliant quality management system for manufacturing and control, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.