Description

4-(Chloromethyl)Benzoic Acid is a versatile aromatic carboxylic acid derivative featuring a reactive chloromethyl group, making it a valuable bifunctional building block in organic synthesis. This compound is essential for creating complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought after by research institutions and industrial manufacturers involved in developing active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug molecules, including potential candidates for cardiovascular and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural modification.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or cross-linking agent in the manufacture of specialty polymers, resins, and liquid crystal materials.
• Peptide & Bioconjugation Chemistry: The chloromethyl group facilitates attachment to other molecules, useful in creating peptide mimics and antibody-drug conjugates (ADCs).
• Organic Synthesis Building Block: Employed in nucleophilic substitution and further functionalization reactions to introduce benzoic acid moieties into target molecules.
• Material Science Research: Investigated for use in metal-organic frameworks (MOFs) and other advanced functional materials due to its dual functionality.

Basic Information

Product Name	4-(Chloromethyl)Benzoic Acid
CAS No.	1642-81-5
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	p-(Chloromethyl)benzoic acid; 4-Carboxybenzyl chloride; (4-Chloromethyl)benzoic acid; Benzoic acid, 4-(chloromethyl)-; p-Carboxybenzyl chloride; Terephthalic acid monochloromethyl ester; α-Chloro-p-toluic acid
EINECS	216-709-6

Quality Control

Our 4-(Chloromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets high-grade specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to the reactive chloromethyl group, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	195°C - 200°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.