Description

(E)-4-Pyridinecarbaldehyde Oxime CAS NO 1637-52-1 is a high-purity organic compound belonging to the pyridine oxime class, serving as a critical synthetic intermediate and ligand in advanced chemical synthesis. Its defined stereochemistry and functional groups make it a valuable building block for constructing complex molecules in pharmaceutical and agrochemical research. This product is essential for R&D chemists and process development scientists working in medicinal chemistry, catalysis, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyridine or oxime functionalities.
• Ligand in Catalysis: Used as a chelating ligand in transition metal catalysis for various organic transformations, including cross-coupling reactions.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides.
• Chemical Research & Development: Versatile reagent for constructing heterocyclic compounds and exploring new synthetic methodologies in academic and industrial labs.
• Coordination Chemistry: Serves as a precursor for metal-organic frameworks (MOFs) and other coordination polymers.

Basic Information

Product Name	(E)-4-Pyridinecarbaldehyde Oxime
CAS No.	1637-52-1
Molecular Formula	C6H6N2O
Molecular Weight	122.12 g/mol
Synonyms	4-Pyridinecarboxaldehyde oxime; Isonicotinaldehyde oxime; p-Pyridinealdoxime; 4-Pyridylaldoxime; (E)-Isonicotinaldehyde oxime; 4-Pyridinealdehyde oxime; 4-Pyridylformaldoxime; 4-Pyridinecarboxaldehyde, oxime
EINECS	216-679-6

Quality Control

Our (E)-4-Pyridinecarbaldehyde Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.