Description

5-Pyrazolecarboxylic Acid CAS NO 1621-91-6 is a versatile heterocyclic building block and key organic intermediate. Its pyrazole core functionalized with a carboxylic acid group makes it a critical synthon for constructing more complex molecules in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of modern pesticides, herbicides, and fungicides, where the pyrazole moiety contributes to biological activity.
• Ligand and Catalyst Development: Employed in coordination chemistry to create novel ligands for metal catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Acts as a monomer or functionalizing agent in the production of specialty polymers, dyes, and organic electronic materials.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & R&D Laboratories: A fundamental research chemical for exploring new organic reactions and heterocyclic chemistry in university and industrial R&D settings.

Basic Information

Product Name	5-Pyrazolecarboxylic Acid
CAS No.	1621-91-6
Molecular Formula	C4H4N2O2
Molecular Weight	112.09 g/mol
Synonyms	1H-Pyrazole-5-carboxylic acid; Pyrazole-5-carboxylic acid; 5-Carboxypyrazole; 1H-Pyrazole-3-carboxylic acid (tautomeric form); 3-Pyrazolecarboxylic acid; Pyrazole-3-carboxylic acid; 1,2-Diazole-5-carboxylic acid; 5-Pyrazolylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Pyrazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	255°C - 265°C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.