Description

1,2-Diiodo-4-Nitrobenzene is a halogenated nitroaromatic compound of significant interest in advanced organic synthesis. This high-purity intermediate is valued for its dual iodine substituents, which serve as excellent leaving groups and cross-coupling partners, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the nitro and iodo functionalities are crucial for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for creating biaryl and other complex structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile reagent for exploring new synthetic methodologies and creating specialized chemical libraries.
• Dye and Pigment Intermediate: Acts as a starting material in the synthesis of specialized dyes and pigments that require nitro and halogen groups for color and stability properties.

Basic Information

Product Name	1,2-Diiodo-4-Nitrobenzene
CAS No.	1608-46-4
Molecular Formula	C6H3I2NO2
Molecular Weight	390.90 g/mol
Synonyms	4-Nitro-1,2-diiodobenzene; 1,2-Diiodo-4-nitrobenzene; 4-Nitro-o-diiodobenzene; Benzene, 1,2-diiodo-4-nitro-; o-Diiodonitrobenzene; NSC 403119; 1,2-Diiodo-4-nitro-benzene
EINECS	Contact for details

Quality Control

Our 1,2-Diiodo-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.