Description

1-(2-Hydroxy-Ethyl)-Pyrrole-2,5-Dione is a versatile N-substituted maleimide derivative, a key building block in organic synthesis and polymer chemistry. Its bifunctional nature, featuring both a reactive maleimide group and a hydroxylethyl side chain, makes it a valuable intermediate for creating advanced materials with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel compounds, cross-linkers, or functionalized polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring maleimide-based conjugation or functionalization.
• Polymer Cross-Linking Agent: Utilized to modify and cross-link polymers, enhancing thermal stability, mechanical strength, and chemical resistance in coatings, adhesives, and composite materials.
• Bioconjugation Reagent: Acts as a linker for attaching molecules (e.g., drugs, dyes, peptides) to proteins, antibodies, or other biomolecules due to the selective reactivity of the maleimide group with thiols.
• Agrochemical Synthesis: Employed as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Specialty Chemical Manufacturing: Used to synthesize a wide range of specialty chemicals, including corrosion inhibitors, surfactants, and photographic chemicals.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new organic reactions and creating novel molecular architectures.

Basic Information

Product Name	1-(2-Hydroxy-Ethyl)-Pyrrole-2,5-Dione
CAS No.	1585-90-6
Molecular Formula	C6H7NO3
Molecular Weight	141.12 g/mol
Synonyms	N-(2-Hydroxyethyl)maleimide; 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione; 2,5-Pyrrolidinedione, 1-(2-hydroxyethyl)-; N-Hydroxyethylmaleimide; HEMI; Maleimide N-hydroxyethyl; N-(β-Hydroxyethyl)maleimide
EINECS	216-426-5

Quality Control

Our 1-(2-Hydroxy-Ethyl)-Pyrrole-2,5-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong bases and reducing agents. The product may be hygroscopic; handle under an inert atmosphere if necessary for sensitive applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	74 - 78 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.