Description

4-Hydroxybenzenesulfonamide is a versatile organic intermediate and building block in fine chemical synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, dyes, and functional materials. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production for creating sulfonamide derivatives and other high-value compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing various sulfonamide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents that utilize the sulfonamide functional group.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating azo dyes and other colorants where the phenolic and sulfonamide groups contribute to chromophore properties.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including resins and materials with specific functional properties.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new organic reactions and developing novel chemical entities.
• Cross-coupling Reactions: Useful substrate in palladium-catalyzed and other metal-mediated coupling reactions to create complex biaryl structures.

Basic Information

Product Name	4-Hydroxybenzenesulfonamide
CAS No.	1576-43-8
Molecular Formula	C6H7NO3S
Molecular Weight	173.19 g/mol
Synonyms	p-Hydroxybenzenesulfonamide; 4-Hydroxybenzenesulfonic acid amide; Phenol-4-sulfonamide; Benzenesulfonamide, 4-hydroxy-; p-Phenolsulfonamide; 4-Sulfamoylphenol; 1-Hydroxy-4-sulfamoylbenzene; EINECS 216-401-3
EINECS	216-401-3

Quality Control

Our 4-Hydroxybenzenesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.