Description

[1R-(1Alpha,2Beta,5Alpha)]-1-(Isopropyl)-2-Methoxy-4-Methylcyclohexane is a high-purity, stereochemically defined cyclohexane derivative used as a critical chiral intermediate in advanced organic synthesis. This compound is valued for its defined three-dimensional structure, which is essential for imparting specific biological activity or material properties in final products. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries for the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is crucial for efficacy.
• Flavor & Fragrance Ingredient: Serves as a precursor for high-value aroma chemicals, contributing unique olfactory notes due to its methoxy and alkyl-substituted cyclohexane structure.
• Material Science Research: Employed as a monomer or modifier in the development of specialized polymers and liquid crystals.
• Catalyst & Ligand Development: Acts as a scaffold for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	[1R-(1Alpha,2Beta,5Alpha)]-1-(Isopropyl)-2-Methoxy-4-Methylcyclohexane
CAS No.	1565-76-0
Molecular Formula	C11H22O
Molecular Weight	170.29 g/mol
Synonyms	(1R,2S,5R)-1-Isopropyl-2-methoxy-4-methylcyclohexane; (1R,2S,5R)-2-Methoxy-1-(1-methylethyl)-4-methylcyclohexane; 1-(1-Methylethyl)-2-methoxy-4-methylcyclohexane, (1R,2S,5R)-; (-)-Menthyl methyl ether (specific isomer); p-Menth-2-yl methyl ether; 4-Methyl-1-(propan-2-yl)-2-methoxycyclohexane; 1-Isopropyl-2-methoxy-4-methylcyclohexane (stereoisomer)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for chiral intermediates. Each batch is characterized to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) are provided, detailing key parameters such as enantiomeric excess (ee), diastereomeric excess (de), and chemical assay. We support cGMP and ISO 9001 compliant manufacturing practices for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 97.0%
Diastereomeric Purity (GC/HPLC)	≥ 98.0% de
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.