Description

Difluoromethanesulphonyl Chloride is a highly reactive organosulfur compound primarily used as a key fluorinated building block in advanced organic synthesis. Its value lies in its ability to introduce the difluoromethanesulfonyl group, a versatile moiety for constructing complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent for synthesizing sulfonamide-based drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that benefit from the stability and lipophilicity imparted by the fluorinated sulfonyl group.
• Material Science: Serves as a monomer or modifier in the creation of specialty polymers, coatings, and electrolytes with enhanced chemical resistance and performance.
• Chemical Research: Employed as a versatile electrophile and fluorinating agent in organic synthesis for constructing C-S bonds and introducing fluorinated functionalities.
• Ligand and Catalyst Development: Useful for preparing novel sulfonyl-containing ligands for metal catalysis and organocatalysis.

Basic Information

Product Name	Difluoromethanesulphonyl Chloride
CAS No.	1512-30-7
Molecular Formula	CHClF2O2S
Molecular Weight	150.53 g/mol
Synonyms	Difluoromethanesulfonyl Chloride; Difluoromethylsulfonyl Chloride; Chlorodifluoromethanesulfonate; NSC 403058; Methanesulfonyl chloride, difluoro-; α,α-Difluoromethanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our Difluoromethanesulphonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including assay (by GC/HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.