Description

3-o-Methylquercetin is a methylated derivative of the flavonoid quercetin, known for its enhanced metabolic stability and bioavailability. This compound serves as a crucial reference standard and biochemical research tool for studying flavonoid metabolism, enzyme inhibition, and antioxidant mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, nutraceutical formulators, and academic research institutions focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of flavonoid metabolites in drug development and pharmacokinetic studies.
• Biochemical Research: Acts as a key inhibitor and probe for studying enzymes like catechol-O-methyltransferase (COMT) and other methyltransferases.
• Nutraceutical & Cosmetic Ingredient: Incorporated into advanced formulations for its potential antioxidant and skin-protective properties, leveraging its improved stability over quercetin.
• Academic Research: Essential for investigations into flavonoid chemistry, structure-activity relationships (SAR), and natural product biosynthesis.
• Analytical Chemistry: Serves as a high-purity calibration standard for HPLC, LC-MS, and other chromatographic methods in analytical laboratories.

Basic Information

Product Name	3-o-Methylquercetin
CAS No.	1486-70-0
Molecular Formula	C₁₇H₁₄O₇
Molecular Weight	330.29 g/mol
Synonyms	3-O-Methylquercetin; Quercetin 3-methyl ether; 3-Methoxyquercetin; Isorhamnetin; 3'-Methoxy-3,4',5,7-tetrahydroxyflavone; 5,7,3',4'-Tetrahydroxy-3-methoxyflavone; Tamarixetin; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-o-Methylquercetin is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.