Description

2,5-Dimethoxybenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, introducing the sulfonyl functional group to create sulfonamides and sulfonate esters with high efficiency. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials. Its specific substitution pattern offers unique reactivity and selectivity for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Dye and Pigment Manufacturing: Serves as a precursor for sulfonated dyes and pigments, improving solubility and color fastness.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce sulfonyl groups into polymers, altering their physical and chemical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Ligand and Catalyst Design: Useful for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,5-Dimethoxybenzenesulfonyl Chloride
CAS No.	1483-28-9
Molecular Formula	C8H9ClO4S
Molecular Weight	236.67 g/mol
Synonyms	1,4-Dimethoxy-2-sulfonylchloridobenzene; 2,5-Dimethoxybenzenesulfonyl chloride; 2,5-Dimethoxyphenylsulfonyl chloride; Benzenesulfonyl chloride, 2,5-dimethoxy-; 2,5-Dimethoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,5-Dimethoxybenzenesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We are committed to meeting the stringent requirements of research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.