Description

1-Methyl-3-Trifluoromethyl-2-Pyrazolin-5-One is a versatile fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity and properties imparted by the trifluoromethyl and pyrazolone functional groups, enabling the development of high-performance materials and active ingredients. This intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science: Acts as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and thermal stability.
• Chemical Research: Employed in organic synthesis as a versatile scaffold for constructing complex heterocycles and in catalysis studies.
• Dye and Pigment Industry: Serves as an intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and light stability properties.

Basic Information

Product Name	1-Methyl-3-Trifluoromethyl-2-Pyrazolin-5-One
CAS No.	1481-02-3
Molecular Formula	C5H5F3N2O
Molecular Weight	166.10 g/mol
Synonyms	3-Trifluoromethyl-1-methyl-2-pyrazolin-5-one; 1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one; 5-Methyl-3-(trifluoromethyl)pyrazole; 3-Trifluoromethyl-1-methyl-5-pyrazolone; 1-Methyl-3-trifluoromethyl-5-pyrazolone; 1481-02-3; 3-(Trifluoromethyl)-1-methyl-1H-pyrazol-5(4H)-one
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Trifluoromethyl-2-Pyrazolin-5-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our production adheres to cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.