Description

3-[(2-Hydroxyethyl)Thio]Propane-1,2-Diol is a versatile sulfur-containing diol, also known as 2-Hydroxyethylthio-1,3-propanediol, with significant utility as a chemical intermediate and functional additive. Its bifunctional structure, featuring both hydroxyl and thioether groups, makes it valuable for introducing polarity, hydrophilicity, and sulfur-based reactivity into target molecules. This compound is particularly sought after by manufacturers in the pharmaceutical, polymer, and specialty chemical sectors for applications ranging from synthesis to material modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where the thioether and hydroxyl functionalities can be leveraged for conjugation or to modulate solubility and bioavailability.
• Polymer & Resin Modifier: Acts as a chain extender, cross-linking agent, or hydrophilic modifier in the production of polyurethanes, epoxy resins, and other specialty polymers to enhance flexibility, adhesion, or moisture resistance.
• Lubricant & Fuel Additive: Serves as a precursor or component in formulating extreme pressure additives, corrosion inhibitors, and stabilizers for industrial lubricants and functional fluids.
• Cosmetic & Personal Care Ingredient: Employed as a humectant, solvent, or carrier in formulations for skin care and hair care products due to its hygroscopic and solubilizing properties.
• Chemical Synthesis Building Block: A key starting material or intermediate for synthesizing more complex sulfur-containing compounds, including ligands, surfactants, and chelating agents.
• Photographic & Imaging Chemicals: Utilized in the formulation of certain photographic developers and other imaging chemicals where its reducing and solubilizing characteristics are beneficial.

Basic Information

Product Name	3-[(2-Hydroxyethyl)Thio]Propane-1,2-Diol
CAS No.	1468-40-2
Molecular Formula	C5H12O3S
Molecular Weight	152.21 g/mol
Synonyms	2-Hydroxyethylthio-1,3-propanediol; 1,3-Propanediol, 2-[(2-hydroxyethyl)thio]-; 2-[(2-Hydroxyethyl)thio]-1,3-propanediol; 3-Hydroxy-2-[(2-hydroxyethyl)thio]propyl alcohol; Thioglycerol hydroxyethyl ether; HEPT; Glyceryl hydroxythioethyl ether
EINECS	215-981-7

Quality Control

Our 3-[(2-Hydroxyethyl)Thio]Propane-1,2-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets precise specifications for identity, purity, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, water content, and specific impurities. Our quality commitment supports applications requiring high-purity intermediates, including those under cGMP guidelines for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture. Separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.510 - 1.520
Density (20°C)	1.20 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.