Description

trans-1,2-Cyclohexanediol is a high-purity, stereochemically defined diol compound widely utilized as a versatile chiral building block in advanced organic synthesis. Its rigid cyclohexane backbone and vicinal hydroxyl groups in the trans configuration make it a valuable precursor for pharmaceuticals, agrochemicals, and specialty polymers. This compound is essential for research and production chemists in fine chemical, pharmaceutical, and material science industries seeking to introduce specific stereochemistry and functionality into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating molecules with defined stereocenters.
• Ligand and Catalyst Preparation: Used to synthesize chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing polyesters, polycarbonates, and other specialty polymers with enhanced thermal and mechanical properties.
• Agrochemical Synthesis: An intermediate in the production of herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Employed as a precursor for musk and other cyclic fragrance compounds.
• Research & Development: A valuable standard and starting material in academic and industrial R&D for methodological studies and novel compound discovery.

Basic Information

Product Name	trans-1,2-Cyclohexanediol
CAS No.	1460-57-7
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(1R,2R)-1,2-Cyclohexanediol; (1R,2R)-Cyclohexane-1,2-diol; trans-(±)-1,2-Cyclohexanediol; (±)-trans-1,2-Cyclohexanediol; rac-trans-1,2-Cyclohexanediol; 1,2-Cyclohexanediol, trans-; Cyclohexane-1,2-diol, (1R,2R)-rel-
EINECS	215-962-0

Quality Control

Our trans-1,2-Cyclohexanediol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% trans isomer
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.