Description

Dimethyl Bicyclo[2.2.2]Octane-1,4-Dicarboxylate is a high-purity, synthetically valuable diester derivative of the rigid bicyclo[2.2.2]octane scaffold. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, prized for its unique three-dimensional structure that imparts specific steric and electronic properties to target molecules. It is essential for research and production teams in pharmaceutical development, agrochemical synthesis, and advanced material science who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) with complex, three-dimensional frameworks, particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the bicyclic structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, dendrimers, and metal-organic frameworks (MOFs) due to its rigid, multi-functional geometry.
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions, cross-coupling reactions, and other transformations to introduce the sterically constrained bicyclo[2.2.2]octane unit.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical space in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	Dimethyl Bicyclo[2.2.2]Octane-1,4-Dicarboxylate
CAS No.	1459-96-7
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	1,4-Bicyclo[2.2.2]octanedicarboxylic Acid Dimethyl Ester; Dimethyl 1,4-Bicyclo[2.2.2]octanedicarboxylate; Bicyclo[2.2.2]octane-1,4-dicarboxylic Acid Dimethyl Ester; 1,4-Dimethoxycarbonylbicyclo[2.2.2]octane; DMBO; Dimethyl BCO-1,4-Dicarboxylate
EINECS	Contact for details

Quality Control

Our Dimethyl Bicyclo[2.2.2]Octane-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for use in sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.