Description

(R)-1-Phenyl-1-Chloroethane is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its defined stereochemistry, which is crucial for imparting specific biological activity and properties in the final target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereoisomer can affect efficacy and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D: A valuable reagent in university and corporate research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-1-Phenyl-1-Chloroethane
CAS No.	1459-15-0
Molecular Formula	C8H9Cl
Molecular Weight	140.61 g/mol
Synonyms	(R)-(-)-1-Chloro-1-phenylethane; (R)-α-Chloroethylbenzene; (R)-1-Chloro-1-phenylethane; (R)-Phenylethyl Chloride; (R)-Sec-Phenethyl Chloride; (R)-Styryl Chloride; (R)-1-Phenylethyl Chloride; (R)-(-)-α-Phenylethyl Chloride
EINECS	Contact for details

Quality Control

Our (R)-1-Phenyl-1-Chloroethane is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.