Description

Pyridine-2-Carboxylic Acid Hydrazide is a versatile heterocyclic hydrazide derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmacologically active molecules and functional materials. Industries that need it include pharmaceutical R&D for creating new drug candidates, agrochemical manufacturing for novel crop protection agents, and academic research focused on coordination chemistry and catalysis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with pyridine-based cores, such as antimicrobial and anti-tuberculosis agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its hydrazide functionality enables the creation of compounds with specific biological activity.
• Ligand in Coordination Chemistry: Acts as a chelating ligand for transition metals (e.g., Cu, Ni, Co) in the preparation of catalysts and metal-organic frameworks (MOFs) for industrial and research applications.
• Corrosion Inhibitor Formulation: Employed in the development of high-performance corrosion inhibitors for industrial cooling systems and metal surface treatment processes.
• Polymer Additive: Functions as a stabilizer or cross-linking agent in specialty polymer systems to enhance thermal and chemical resistance.
• Analytical Reagent: Utilized in analytical chemistry as a derivatization agent for the detection and quantification of carbonyl compounds via spectrophotometric methods.

Basic Information

Product Name	Pyridine-2-Carboxylic Acid Hydrazide
CAS No.	1452-57-9
Molecular Formula	C6H7N3O
Molecular Weight	137.14 g/mol
Synonyms	Picolinic Acid Hydrazide; 2-Pyridinecarboxylic Acid Hydrazide; Picolinohydrazide; Picolinic Hydrazide; Isonicotinic Acid Hydrazide Isomer; 2-Picolinoylhydrazine; Pyridine-2-Carbohydrazide; Picolinoyl Hydrazide
EINECS	215-908-6

Quality Control

Our Pyridine-2-Carboxylic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	160 - 165 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.