Description

1,3-Dibromo-5-Fluorobenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty polymers.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the fluorine and bromine substituents confer specific biological activity and stability.
• Liquid Crystal Materials (LCs): Serves as a core structural unit in the production of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed as a precursor for electron-transport materials and host materials in OLED device fabrication.
• Specialty Polymer Monomer: Used to introduce halogenated phenyl groups into high-performance polymers, influencing their thermal and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Product Name	1,3-Dibromo-5-Fluorobenzene
CAS No.	1435-51-4
Molecular Formula	C6H3Br2F
Molecular Weight	253.89 g/mol
Synonyms	5-Fluoro-1,3-dibromobenzene; 1,3-Dibromo-5-fluorobenzene; 3,5-Dibromofluorobenzene; 5-Fluororesorcinol dibromide; Benzene, 1,3-dibromo-5-fluoro-; m-Dibromo-p-fluorobenzene; NSC 403126
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-5-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.