Description

3-Acetyl-2-Oxazolidinone is a versatile heterocyclic building block and chiral auxiliary of significant importance in synthetic organic chemistry. Its value lies in its ability to facilitate stereoselective transformations, enabling the synthesis of complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of β-amino acids, β-lactams, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Auxiliary: Employed in Evans aldol and related reactions to induce diastereoselectivity in carbon-carbon bond formation.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Peptidomimetics: Used in the construction of conformationally constrained peptide analogs for drug discovery.

Basic Information

Product Name	3-Acetyl-2-Oxazolidinone
CAS No.	1432-43-5
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	N-Acetyl-2-oxazolidinone; 1-Acetyl-2-oxazolidinone; 2-Oxazolidinone, 3-acetyl-; 3-Acetyloxazolidin-2-one; Acetyloxazolidinone; Evans Auxiliary Derivative; (R/S)-3-Acetyl-2-oxazolidinone
EINECS	215-857-5

Quality Control

Our 3-Acetyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Melting Point	Approx. 78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.