Description

(-)-Epicatechin Gallate CAS NO 1257-08-5 is a high-purity, naturally derived polyphenol belonging to the catechin family. This compound is valued for its potent antioxidant and bioactive properties, making it a critical ingredient for advanced research and product development. It is primarily sought by manufacturers and researchers in the nutraceutical, pharmaceutical, and cosmetic industries for applications requiring standardized botanical extracts and active ingredients.

Application

• Nutraceutical & Dietary Supplements: Used as a key active ingredient in formulations targeting oxidative stress, cardiovascular health, and metabolic support.
• Pharmaceutical Research: Serves as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for its anti-inflammatory and neuroprotective effects.
• Cosmetics & Skincare: Incorporated into anti-aging serums, creams, and lotions for its antioxidant capacity to protect skin from environmental damage.
• Functional Food & Beverages: Added to health drinks, fortified foods, and sports nutrition products to enhance their antioxidant profile.
• Biochemical Research: Utilized in cell culture studies and enzymatic assays to investigate mechanisms of action related to its bioactivity.
• Standardized Botanical Extracts: Acts as a marker compound for the quality control and standardization of green tea and other plant-derived extracts.

Basic Information

Product Name	(-)-Epicatechin Gallate
CAS No.	1257-08-5
Molecular Formula	C22H18O10
Molecular Weight	442.37 g/mol
Synonyms	(-)-Epicatechin 3-gallate; ECG; Epicatechin gallate; L-Epicatechin gallate; 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate); Catechin, 3-gallate, (-)-; Epigallocatechin (common misnomer, clarify); Tea catechin gallate
EINECS	215-025-3

Quality Control

Our (-)-Epicatechin Gallate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications. Production can adhere to cGMP guidelines for pharmaceutical and nutraceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, desiccate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.