Description

2′-Chloro[1,1′-Biphenyl]-4-Amine is a specialized aromatic amine derivative, serving as a crucial building block in advanced organic synthesis. Its molecular structure, featuring a biphenyl core with chloro and amine substituents, makes it a valuable intermediate for creating complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its biphenyl structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized azo dyes and high-performance pigments requiring specific lightfastness and color properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to form complex carbon-nitrogen bonds.

Basic Information

Product Name	2′-Chloro[1,1′-Biphenyl]-4-Amine
CAS No.	1204-42-8
Molecular Formula	C12H10ClN
Molecular Weight	203.67 g/mol
Synonyms	2'-Chlorobiphenyl-4-amine; 4-Amino-2'-chlorobiphenyl; 2-Chloro-4-aminobiphenyl; (2-Chlorophenyl)aniline; 2'-Chloro-4-aminobiphenyl; 2-Chloro-4-phenylaniline; Biphenyl-4-amine, 2'-chloro-; 4-Amino-2'-chloro-1,1'-biphenyl
EINECS	214-882-5

Quality Control

Our 2′-Chloro[1,1′-Biphenyl]-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity while monitoring for key impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.