Description

cis-4-Aminomethylcyclohexane-1-Carboxylic Acid is a versatile, conformationally constrained amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a primary amine functional group on a rigid cyclohexane backbone, makes it invaluable for creating novel compounds with specific stereochemical and spatial properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetics & Bioactive Molecule Design: Used to introduce conformational rigidity into peptide backbones, enhancing stability and biological activity.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides and plant growth regulators with improved selectivity.
• Chiral Catalyst & Ligand Preparation: Serves as a precursor for synthesizing sophisticated chiral auxiliaries and ligands used in asymmetric catalysis.
• Specialty Polymer Modification: Functional monomer for creating polyamides and other polymers with tailored thermal and mechanical properties.
• Research & Development: A valuable tool compound in academic and industrial R&D for exploring structure-activity relationships (SAR).

Basic Information

Product Name	cis-4-Aminomethylcyclohexane-1-Carboxylic Acid
CAS No.	1197-17-7
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	cis-4-(Aminomethyl)cyclohexanecarboxylic Acid; (1r,4r)-4-(Aminomethyl)cyclohexanecarboxylic Acid; 4-Aminomethylcyclohexanecarboxylic Acid (cis-); 4-Carboxycyclohexylmethylamine; NSC 3349; trans-4-Aminomethylcyclohexanecarboxylic Acid (common misnomer); cis-ACCA; cis-4-ACCA
EINECS	214-823-5

Quality Control

Our cis-4-Aminomethylcyclohexane-1-Carboxylic Acid CAS NO 1197-17-7 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.