Description

D-(-)-3-Thienylglycine is a non-proteinogenic amino acid derivative featuring a thiophene ring, a key chiral building block in organic synthesis. Its unique structure makes it a valuable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily utilized in the research and development of pharmaceuticals, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetics: Used in the design and synthesis of peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective chemical reactions.
• Agrochemical Research: A potential building block for developing new crop protection agents and herbicides.
• Material Science: Can be incorporated into specialty polymers or organic electronic materials due to the conductive properties of the thiophene moiety.
• Biochemical Research: Used in studies of enzyme mechanisms and as a substrate analog in metabolic pathway investigations.

Basic Information

Product Name	D-(-)-3-Thienylglycine
CAS No.	1194-86-1
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	(R)-2-Amino-2-(thiophen-3-yl)acetic acid; D-3-Thienylglycine; (R)-3-Thienylglycine; D-α-Amino-3-thiopheneacetic acid; (R)-2-Amino-2-(3-thienyl)acetic acid; D-(-)-2-Amino-2-(3-thienyl)ethanoic acid; 3-Thienyl-D-glycine
EINECS	214-795-7

Quality Control

Our D-(-)-3-Thienylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D- isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.