Description

(2S,3S)-2,3-Dibromo-5α-Cholestane CAS NO 1175-10-6 is a high-purity, stereochemically defined brominated sterane derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of complex bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control and reliable quality for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroid-based therapeutics and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of specialized plant growth regulators or pesticides where the sterane skeleton provides a bioactive core.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and total synthesis projects to introduce specific bromine atoms and chiral centers into complex molecular architectures.
• Biochemical Probe Development: Utilized in the creation of labeled or modified sterol analogs for studying biological membrane interactions and enzyme mechanisms.
• Material Science Research: Acts as a precursor for the synthesis of liquid crystals or other functional organic materials with specific steric and electronic properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S,3S)-2,3-Dibromo-5α-Cholestane
CAS No.	1175-10-6
Molecular Formula	C₂₇H₄₆Br₂
Molecular Weight	530.47 g/mol
Synonyms	5α-Cholestane-2β,3β-diol dibromide; 2β,3β-Dibromocholestane; (2β,3β)-Dibromo-5α-cholestane; 2,3-Dibromo-5α-cholestane; Cholestane-2,3-diol dibromide; 5α-Cholestan-2β,3β-diyldibromide; 2,3-Dibromocholestane; NSC 61759
EINECS	Contact for details

Quality Control

Our (2S,3S)-2,3-Dibromo-5α-Cholestane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and other relevant physicochemical analyses. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% de
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.