Description

4-Acetamidothiophenol is a versatile sulfur-containing aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a thiol and an acetamide group, makes it a valuable intermediate for constructing complex molecules with specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials. We supply high-purity 4-Acetamidothiophenol to support innovation and reliable production processes globally.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and fungicides.
• Material Science: Used in the development of specialty polymers, ligands for catalysis, and functionalized surfaces.
• Chemical Research: Essential reagent in organic chemistry for constructing sulfur-heterocycles and conducting thiol-based coupling reactions.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating agents and catalysts used in asymmetric synthesis.
• Bioconjugation Chemistry: Utilized for modifying proteins, peptides, and other biomolecules via its reactive thiol group.

Basic Information

Product Name	4-Acetamidothiophenol
CAS No.	1126-81-4
Molecular Formula	C8H9NOS
Molecular Weight	167.23 g/mol
Synonyms	N-(4-Mercaptophenyl)acetamide; p-Acetamidothiophenol; 4-Acetamidobenzenethiol; 4-Mercaptoacetanilide; Acetamide, N-(4-mercaptophenyl)-; 4-Thioacetamidoaniline; p-Thioacetamidoaniline; 4-Acetylaminothiophenol
EINECS	214-423-8

Quality Control

Our 4-Acetamidothiophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.