Description

1,4-Dichlorobicyclo[2.2.2]octane CAS NO 1123-39-3 is a specialized bicyclic organic compound featuring a rigid, cage-like structure with chlorine substituents at the 1 and 4 positions. This unique molecular architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for creating complex three-dimensional frameworks. It is primarily sought after by pharmaceutical researchers, agrochemical developers, and material scientists for applications in drug discovery, ligand design, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring rigid, three-dimensional scaffolds to enhance binding specificity and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents, where its bicyclic structure can contribute to the efficacy and environmental profile of new herbicides or insecticides.
• Ligand and Catalyst Development: Acts as a precursor for designing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers, dendrimers, and metal-organic frameworks (MOFs) to impart unique structural and physical properties.
• Organic Synthesis Building Block: Provides a versatile, rigid core for constructing complex natural product analogs and other high-value fine chemicals in research laboratories.

Basic Information

Product Name	1,4-Dichlorobicyclo[2.2.2]octane
CAS No.	1123-39-3
Molecular Formula	C8H12Cl2
Molecular Weight	179.09 g/mol
Synonyms	1,4-Dichlorobicyclo[2.2.2]octane; Bicyclo[2.2.2]octane, 1,4-dichloro-; 1,4-Dichloroadamantane (common misnomer); 1,4-Dichlorotricyclo[2.2.2.02,6]octane; DACO; p-Dichlorobicyclooctane; 1,4-Dichlorocubane precursor analog
EINECS	214-373-1

Quality Control

Our 1,4-Dichlorobicyclo[2.2.2]octane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting requirements of research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.